Tutorials

In the context of telehealth and internet of things (IOT), there are unprecedented needs for developing remote diagnostic tools that can monitor chemical and biological markers remotely anytime anywhere, such as via a smart phone. Such sensing devices are ideally soft and thin so that they can “bio-friendly” interface with soft biological systems. In this talk, I will present our skin-like sensing devices that can remotely monitor human’s health and cardiac organoids.

In the past 3 decades, there were many attempts to leverage integrated circuit technologies, particularly CMOS fabrication processes, to create unique biosensors capable of detecting nucleic acid molecules, proteins, and other biological and chemical analytes. While such efforts targeted a diverse set of biotechnology applications, they all shared a common motivation. CMOS biosensors (or CMOS biochips) hold the promise of delivering superior analytical accuracy alongside scalability, cost efficiency and manufacturability. Yet, the outcomes of such endeavors have been varied, and the implementation of these multidisciplinary systems has proven to be significantly more challenging and complex than initially anticipated.